MINtS lung cancer multi-3CDx(Reference information available)

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gene-related test
genetic tests for malignant tumor (solid tumor)
MINtS lung cancer multi-3CDx
(Reference information available)

Laboratory：Akiruno

○MINtS lung cancer multi-3CDx
(Reference information available)

CODE：00E28 6

TEST NAME SPECIMEN
REQUIREMENT
（ｍL） CONTAINER CAP COLOR STORE
TEMPERATURE
(STABILITY) TURNAROUND
TIME (DAY) METHODOLOGY REFERENCE RANGE
(UNIT)
MINtS lung cancer multi-3CDx
(Reference information available)
pleural effusion
4.0
ARR
（14 days）
13-20 Next Generation Sequencing (NGS)
A method that uses a next-generation sequencer to simultaneously determine the base sequences of a huge number of DNA fragments.

COMMENT

The purpose of this test is to detectEGFR gene mutations, ALK fusion genes, and BRAF gene V600E mutations using nucleic acids extracted from cancer tissue, and to determine the suitability of drugs for non-small cell lung cancer. We will also report the analysis results, which have not been approved by pharmaceutical regulations, for research purposes only.
The recommended percentage of tumor cells required for testing is 10% or more.
When submitting samples, please follow the detailed sample submission information provided in the ”Cytology Sample Collection and Processing Operation Manual” issued by EIKEN CHEMICAL CO.,LTD.
Please see below for points to note when submitting unstained specimen slides. When submitting unstained specimen slides, please be sure to also submit one HE-stained specimen with the tumor cell area marked.
Please avoid cryopreservation.
Please avoid requests that overlap with other items. This testing method is more susceptible to contamination, so please be careful when handling samples.
●When requesting this test
Please submit the sample according to the sample submission method described in the following document issued by EIKEN CHEMICAL CO.,LTD. for each test material. https://mints.eiken.co.jp/
-Cytological sample collection and processing operation manual
-Quality of cytological samples (guideline for total nucleic acid yield and sample appearance)
-How to submit bronchoscope cytodiagnosis samples
-How to submit pleural effusion samples for carcinomatous pleurisy
-How to submit FFPE samples

CONTAINER

ARR 旧容器記号 r A

滅菌ポリスピッツ

貯蔵方法：室温

supplementary information

対象遺伝子変異等と関連する医薬品および適応がん腫

遺伝子変異等	がん腫	関連する医薬品
EGFR遺伝子変異	非小細胞肺癌	ゲフィチニブ、エルロチニブ塩酸塩、アファチニブマレイン酸塩、オシメルチニブメシル酸塩、ダコミチニブ水和物
ALK融合遺伝子		アレクチニブ塩酸塩、クリゾチニブ、ブリグチニブ、セリチニブ、ロルラチニブ
BRAF遺伝子V600E変異		ダブラフェニブメシル酸塩及びトラメチニブジメチルスルホキシド付加物の併用投与

TEST DIRECTORY