TEST DIRECTORY

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Laboratory：Akiruno

○adrenal medulla hormones

TEST NAME

 SPECIMEN
REQUIREMENT
（ｍL）		 CONTAINER CAP COLOR STORE
TEMPERATURE
(STABILITY)		 TURNAROUND
TIME (DAY)		 METHODOLOGY REFERENCE RANGE
(UNIT)

Total catecholamines

acidic urine storage
2
U00 Refrigeration
（28 days）
 4-6 HPLC

HPLC (High performance liquid chromatography)
High performance liquid chromatography
A method of liquid chromatography that uses a liquid as a mobile phase to achieve high speed and high precision separation using a densely packed column and a high pressure pump.

 52.0-195.3(μg/day)

Catecholamine 3 fractionation
〔A:adrenaline
NA:noradrenaline
DA:dopamine〕

Immediately Refrigerated
Plasma
1.5
PN7
↓
A00 		Freeze
（1 month）
 4-6 HPLC

HPLC (High performance liquid chromatography)
High performance liquid chromatography
A method of liquid chromatography that uses a liquid as a mobile phase to achieve high speed and high precision separation using a densely packed column and a high pressure pump.

 Adrenaline: 100 or less Noradrenaline: 100-450 Dopamine: 20 or less (pg/mL)

Catecholamine 3 fractionation
〔A:adrenaline
NA:noradrenaline
DA:dopamine〕

Cerebrospinal fluid
1.5
A00 Freeze
 4-6 HPLC

HPLC (High performance liquid chromatography)
High performance liquid chromatography
A method of liquid chromatography that uses a liquid as a mobile phase to achieve high speed and high precision separation using a densely packed column and a high pressure pump.

 (pg/mL)

Catecholamine 3 fractionation
〔A:adrenaline
NA:noradrenaline
DA:dopamine〕

acidic urine storage
2
U00 Refrigeration
（28 days）
 4-6 HPLC

HPLC (High performance liquid chromatography)
High performance liquid chromatography
A method of liquid chromatography that uses a liquid as a mobile phase to achieve high speed and high precision separation using a densely packed column and a high pressure pump.

 Adrenaline 3.4-26.9
Noradrenaline 48.6-168.4
Dopamine 365.0-961.5 (μg/day)

Metanephrine/ Normetanephrine, fractionation

acidic urine storage
2
U00 Refrigeration
（28 days）
 4-6 LC/MS/MS

LC/MS/MS (Liquid chromatography tandem mass spectrometry)
Liquid chromatography tandem quadrupole mass spectrometry
Liquid chromatography uses differences in affinity to decompose components of a target substance. , a method in which ions of a specific mass are further separated by mass using a mass spectrometer, dissociated and fragmented, and then these ions are detected.

 Metanephrine 0.04-0.19
Normetanephrine 0.09-0.33
(mg/day)

L-dopa

Immediately Refrigerated
Plasma
1.5
PN7
↓
A00 		Freeze
 5-18 HPLC

HPLC (High performance liquid chromatography)
High performance liquid chromatography
A method of liquid chromatography that uses a liquid as a mobile phase to achieve high speed and high precision separation using a densely packed column and a high pressure pump.

 1.2-2.2(ng/mL)

Dopamine total

Immediately Refrigerated
Plasma
1.5
PN7
↓
A00 		Freeze
 5-18 HPLC

HPLC (High performance liquid chromatography)
High performance liquid chromatography
A method of liquid chromatography that uses a liquid as a mobile phase to achieve high speed and high precision separation using a densely packed column and a high pressure pump.

 1.8-7.7(ng/mL)

Dopamine total

Cerebrospinal fluid
1.5
A00 Freeze
 5-18 HPLC

HPLC (High performance liquid chromatography)
High performance liquid chromatography
A method of liquid chromatography that uses a liquid as a mobile phase to achieve high speed and high precision separation using a densely packed column and a high pressure pump.

 (ng/mL)

HVA

Plasma
1.5
PN7
↓
A00 		Refrigeration
（21 days）
 4-6 HPLC

HPLC (High performance liquid chromatography)
High performance liquid chromatography
A method of liquid chromatography that uses a liquid as a mobile phase to achieve high speed and high precision separation using a densely packed column and a high pressure pump.

 4.4-15.1(ng/mL)

HVA

Cerebrospinal fluid
1.5
A00 Refrigeration
（21 days）
 4-6 HPLC

HPLC (High performance liquid chromatography)
High performance liquid chromatography
A method of liquid chromatography that uses a liquid as a mobile phase to achieve high speed and high precision separation using a densely packed column and a high pressure pump.

 (ng/mL)

HVA

acidic urine storage
1.5
U00 Refrigeration
（28 days）
 4-6 HPLC

HPLC (High performance liquid chromatography)
High performance liquid chromatography
A method of liquid chromatography that uses a liquid as a mobile phase to achieve high speed and high precision separation using a densely packed column and a high pressure pump.

 2.1-6.3(mg/day)

VMA

Plasma
1.5
PN7
↓
A00 		Refrigeration
（21 days）
 4-6 HPLC

HPLC (High performance liquid chromatography)
High performance liquid chromatography
A method of liquid chromatography that uses a liquid as a mobile phase to achieve high speed and high precision separation using a densely packed column and a high pressure pump.

 3.3-8.6(ng/mL)

VMA

acidic urine storage
1.5
U00 Refrigeration
（28 days）
 4-6 HPLC

HPLC (High performance liquid chromatography)
High performance liquid chromatography
A method of liquid chromatography that uses a liquid as a mobile phase to achieve high speed and high precision separation using a densely packed column and a high pressure pump.

 1.5-4.3(mg/day)

Serotonin

Blood (EDTA-2Na added)
1.0
PN2,PN5
↓
A00 		Freeze
 3-16 HPLC

HPLC (High performance liquid chromatography)
High performance liquid chromatography
A method of liquid chromatography that uses a liquid as a mobile phase to achieve high speed and high precision separation using a densely packed column and a high pressure pump.

 57-230(ng/mL)

Serotonin

Immediately Refrigerated
Plasma
1.5
PN7
↓
A00 		Freeze
 3-16 HPLC

HPLC (High performance liquid chromatography)
High performance liquid chromatography
A method of liquid chromatography that uses a liquid as a mobile phase to achieve high speed and high precision separation using a densely packed column and a high pressure pump.

 P(plasma) 0.04-0.35 PRP(platelet rich plasma) 0.17-0.62(μg/mL)

5-HIAA

Plasma
1.5
PN7
↓
A00 		Refrigeration
（25 days）
 4-6 HPLC

HPLC (High performance liquid chromatography)
High performance liquid chromatography
A method of liquid chromatography that uses a liquid as a mobile phase to achieve high speed and high precision separation using a densely packed column and a high pressure pump.

 1.8-6.1(ng/mL)

5-HIAA

Cerebrospinal fluid
1.5
A00 Refrigeration
（25 days）
 4-6 HPLC

HPLC (High performance liquid chromatography)
High performance liquid chromatography
A method of liquid chromatography that uses a liquid as a mobile phase to achieve high speed and high precision separation using a densely packed column and a high pressure pump.

 (ng/mL)

5-HIAA

acidic urine storage
0.5
U00 Refrigeration
（28 days）
 4-6 HPLC

HPLC (High performance liquid chromatography)
High performance liquid chromatography
A method of liquid chromatography that uses a liquid as a mobile phase to achieve high speed and high precision separation using a densely packed column and a high pressure pump.

 1.0-6.0(mg/day)

INACTIVE
MHPG（Suspended beyond orders placed 07-04-2024）

Plasma
1.5
PN7
↓
A00 		Freeze
（35 days）
 Please confirm in advance HPLC

HPLC (High performance liquid chromatography)
High performance liquid chromatography
A method of liquid chromatography that uses a liquid as a mobile phase to achieve high speed and high precision separation using a densely packed column and a high pressure pump.

 3.2～5.9(ng/mL)

INACTIVE
Methanephrine total（Suspended beyond orders placed 03-31-2020）

acidic urine storage
2.0
U00 Freeze
（21 days）
 3-5 HPLC

HPLC (High performance liquid chromatography) Liquid chromatography
Method for high-speed and high-precision separation using liquid chromatography employing a mobile phase with liquid and employing high-density packing columns and high-pressure pumps

 0.13-0.52(mg/day)

INACTIVE
Methanephrine 2 fractionation [
MN:metanephrine
NMN:normetanephrine]（Suspended beyond orders placed 03-31-2020）

acidic urine storage
2.0
U00 Freeze
（21 days）
 3-5 HPLC

HPLC (High performance liquid chromatography) Liquid chromatography
Method for high-speed and high-precision separation using liquid chromatography employing a mobile phase with liquid and employing high-density packing columns and high-pressure pumps

 Metanephrine 0.04-0.19 Normetanephrine 0.09-0.33 (mg/day)

INACTIVE
MHPG（Suspended beyond orders placed 07-04-2024）

Cerebrospinal fluid
1.5
A00 Freeze
 Please confirm in advance HPLC

HPLC (High performance liquid chromatography)
High performance liquid chromatography
A method of liquid chromatography that uses a liquid as a mobile phase to achieve high speed and high precision separation using a densely packed column and a high pressure pump.

 (ng/mL)

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