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immunosuppressive drug

Laboratory：Akiruno

○immunosuppressive drug

TEST NAME	SPECIMEN REQUIREMENT （ｍL）	CONTAINER	CAP COLOR	STORE TEMPERATURE (STABILITY)	TURNAROUND TIME (DAY)	METHODOLOGY	REFERENCE RANGE (UNIT)	BLOOD COLLECTION TIME
Cyclosporine	Blood (EDTA-2K added) 0.7	PKF			2-4	ECLIA ECLIA (Electro chemiluminescence immunoassay) Electro chemiluminescence immunoassay method . A method to measure the luminescence intensity of a ruthenium pyridine complex by reaction.	(ng/mL)	Immediately before next administration (Trough concentration)
Tacrolimus	Blood (EDTA-2K added) 0.7	PKF			2-4	ECLIA ECLIA (Electro chemiluminescence immunoassay) Electro chemiluminescence immunoassay method . A method to measure the luminescence intensity of a ruthenium pyridine complex by reaction.	(ng/mL)	Immediately before next administration (Trough concentration)
Everolimus	Blood (EDTA-2K added) 1.0	PKF			2-4	ECLIA ECLIA (Electro chemiluminescence immunoassay) Electro chemiluminescence immunoassay method . A method to measure the luminescence intensity of a ruthenium pyridine complex by reaction.	When used in combination with cyclosporine as an immunosuppressant Trough 3.0-8 When used as an antineoplastic agent Trough 5-15 (ng/mL)	Immediately before next administration (Trough concentration)
Mycophenolic acid	Plasma 0.5	PN2,PN5 ↓ A00		（7 days）	2-5	Enzyme immunoassay(EIA) EIA (Enzyme immunoassay) Enzyme immunoassay The measurement principle is the same as RIA; an antigen-antibody reaction is performed using an enzyme-labeled antigen or antibody as a labeling substance, and a chromogenic substrate is added to detect enzyme activity. How to measure.	(μg/mL)
Everolimus（Suspended beyond orders placed 06-30-2016）	Blood (EDTA-2K added) 1.0	PK2		（7 days）	2-6	Latex agglutination turbidimetry KIMS (Kinetic Interaction of Microparticles in Solution) A method in which an antigen-antibody reaction is performed using microparticles bound to antigens or antibodies, and the turbidity of the agglutination caused by the antigen-antibody reaction is measured from the transmittance by irradiating it with light.	Trough concentration 3.0-8 (ng/mL) when used in combination with cyclosporine as an immunosuppressant	Immediately before next administration (Trough concentration)