Laboratory：Akiruno
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- myChoice diagnostic system
Laboratory：Akiruno
○myChoice diagnostic system
CODE：08547 6
-
TEST NAME
SPECIMEN
REQUIREMENT
（ｍL） CONTAINER CAP COLOR STORE
TEMPERATURE
(STABILITY) TURNAROUND
TIME (DAY) METHODOLOGY REFERENCE RANGE
(UNIT) -
myChoice diagnostic system
Unstained specimen slide
and
HE stained slide
8 sheets, thickness 5μm
and
1 sheet
Z10
18-23 Next Generation Sequencing (NGS)A method that uses a next-generation sequencer to simultaneously determine the base sequences of a huge number of DNA fragments.
COMMENT
Targets ovarian cancer. When requesting this test, please submit one HE-stained slide along with an unstained specimen slide.
The percentage of tumor cells required for testing is 20% or more. Please see below for points to note when submitting unstained specimen slides.
Please avoid duplicate requests with other items. Please be sure to specify your sex when making your request. This testing method increases the influence of contamination, so please be careful when handling the specimen. The number of days required may vary depending on the measurement and analysis situation.
●What is the myChoice diagnostic system?
Homologous Recombination Deficiency (HRD) and BRCA1, a companion used to detect BRCA2 gene mutations and assist in determining the suitability of niraparib, olaparib alone, or in combination with olaparib and bevacizumab in ovarian cancer patients. It's a diagnosis. The suitability of single-agent olaparib should be determined based solely on the results of BRCA1 and BRCA2 gene mutations.
●About submission
・When requesting this test, please obtain your Myriad account ID in advance.
・Samples cannot be returned. Please note.
●When requesting this inspection
When requesting this inspection, please read the following information and use the special request form.
1. To protect personal information, please anonymize the testee's name and enter it in the ″anonymous code″ field.
2. To confirm that the purpose and limitations of the test and the significance of the BRCA1/2 genes have been explained, and that written consent has been obtained from the test subject. , please check.
3. For inquiries about test results, please use anonymous code.
4. Some of the anonymized personal information will be used by Myriad Genetic Laboratories, Inc. (USA), the measurement and analysis organization for this test, to ensure the quality of the BRCA1/2 genetic test. It may be used to improve.
5. Please check the announcements from related academic societies, etc.
●How to make a request
1. Access the dedicated request input site (https://db.myriadgenetics-ops.com/secure/login.aspx).
2. After logging in, enter the necessary request information according to the ″Myriad Genetics Test Request Input System Operation Guide″.
3. After completing the input, please print out the request form and submit it along with the specimen.
*Internet connection environment is required.
●About unstained specimen slides
Immediately immerse the collected tissue in a 10% neutral buffered formalin solution to fix it (recommended fixation time is 6 to 72 hours). When submitting, please prepare serial sections at the specified thickness from formalin-fixed, paraffin-embedded FFPE (FFPE) blocks prepared within the past 3 years, if possible. Please be careful to avoid contamination by changing the microtome blade for each specimen when slicing. Please note that as nucleic acids are fragmented due to formalin fixation of tissues, analysis may not be possible depending on the type and composition of the fixative, fixation time, and storage condition of the specimen after fixation. .
●About biopsy specimens
Biopsy specimens often contain only a small amount of specimen, and there is a possibility that most of the tissue itself has disappeared or that the tissue has become a piece of tissue that does not contain tumor cells. Please be aware of this in advance.
CONTAINER
![[オブジェクトケース] プレパラート (スライドグラス)](../../common/yoki-images/z10.jpg)
Z10 旧容器記号 t 30
[オブジェクトケース]
プレパラート (スライドグラス)
貯蔵方法：室温
