TEST DIRECTORY

Interpretation of Results of Serologic Reaction Test for Syphilis

* The investigation regarding the presence of any diseases that present with BFP or recent opportunities for infection should be performed.
The progression of STS antibody titers should be monitored, and if a positive reaction to TP antibodies is observed, early syphilis infection is suspected.
Clinical diagnosis is always prioritized, and serological tests are only auxiliary diagnostics.

[Use and Notes of Serologic Reaction Test for Syphilis]

<STS>

The antibody against cardiolipin antigen. It becomes positive in the early stages of syphilis infection and often becomes negative after treatment and reflects syphilis symptoms.
It often causes biological false positive reaction (BFP).

<Biological false positive (BFP)>

STS (RPR) has a high rate of biological false positives (BFP), and in addition to syphilis infection, false positives can also be seen in liver disease, autoimmune disease, and in pregnant women.

<TP antibody>

The antibody against treponema antigen which is the specific antibody observed during syphilis infection.
In the serum of patients who have previously tested positive for syphilis, antibody titers may remain high for an extended period of time.
Nonspecific reaction is observed in rare cases.