Laboratory:Akiruno
- TOP
- gene-related test
- genetic tests related to drug response
- NUDT15 gene codon 139 polymorphism analysis
Laboratory:Akiruno
○NUDT15 gene codon 139 polymorphism analysis
CODE:05881 8
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TEST NAME
SPECIMEN
REQUIREMENT
(mL) CONTAINER CAP COLOR STORE
TEMPERATURE
(STABILITY) TURNAROUND
TIME (DAY) METHODOLOGY REFERENCE RANGE
(UNIT) -
NUDT15 gene codon 139 polymorphism analysis
Blood (EDTA-2Na added)
2.0
PN2,PN5
(3 days)
4-8 PCR (Real Time PCR)Real-time PCR
A type of nucleic acid amplification method based on the basic principle of PCR, which uses oligonucleotides that emit fluorescence upon decomposition to quantify target nucleic acids in real time by checking the fluorescent signal at each PCR cycle. A measurement method that enables
COMMENT
Avoid freezing. This item detects the genetic polymorphism of NUDT15 gene codon139, and the amino acid notation (Arg/Arg, Arg/Cys, Arg/His, Cys/Cys, Cys/His, His/His) We will report on this.
Please avoid duplicate requests with other items.
This testing method increases the influence of contamination, so please be careful when handling the specimen.
PGx target (see below)
Collect the sample in the container shown below, mix well, and store in the refrigerator.
Please avoid duplicate requests with other items.
This testing method increases the influence of contamination, so please be careful when handling the specimen.
CONTAINER
PN2 旧容器記号 C C3 4
EDTA-2Na入り (真空採血量2mL)
内容:EDTA-2Na 3.0mg
貯蔵方法:室温
有効期間:製造から2年
PN5 旧容器記号 C C3 4
EDTA-2Na入り (真空採血量5mL)
内容:EDTA-2Na 7.5mg
貯蔵方法:室温
有効期間:製造から2年
supplementary information
NUDT15遺伝子codon 139多型解析の検出対象
塩基配列 | アミノ酸 | NUDT15遺伝子多型 |
---|---|---|
CGT | アルギニン (Arg) | 野生型 |
TGT | システイン (Cys) | c.415C > T (rs116855232) |
CAT | ヒスチジン (His) | c.416G > A (rs147390019) |