TEST DIRECTORY

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Laboratory：Akiruno

○Brivaracetam

CODE：00W51 2

  • TEST NAME SPECIMEN
    REQUIREMENT
    （ｍL）     CONTAINER CAP COLOR STORE
    TEMPERATURE
    (STABILITY)     TURNAROUND
    TIME (DAY)     METHODOLOGY REFERENCE RANGE
    (UNIT)     BLOOD COLLECTION TIME
  • Brivaracetam
    Immediately
    Plasma
    0.3
    PH5
    ↓
    A00     Refrigeration
    （28 days）
     3-9 LC/MS/MS

    LC/MS/MS (Liquid chromatography tandem mass spectrometry)
    Liquid chromatography tandem quadrupole mass spectrometry
    Liquid chromatography uses differences in affinity to decompose components of a target substance, a method in which ions of a specific mass are further separated by mass using a mass spectrometer, dissociated and fragmented, and then these ions are detected.

     (μg/mL) Immediately before next administration (Trough concentration)

COMMENT



BRIVIACT

Points to note concerning blood collecting containers
Avoid using a container with a serum separating agent. It may effect the results on the drug tests.
Points to note concerning the blood collecting time
1. The blood collecting time is for TDM (therapeutic drug monitoring).
2. In repetitive administration, collect a blood sample after a steady state is achieved.
3. When poisoning is developed, the peak concentration also needs to be measured.
4. The blood collecting time shows the standard time: a patient's condition should be taken into account in collecting a blood sample.

After drawing blood into a container shown in the below image, mix well, and separate plasma within 3 hours.
If 3 hours or longer, the value may be lower. Please refrigerate the plasma samples.

CONTAINER

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