Laboratory:Akiruno

Laboratory:Akiruno
CODE:00T32 6
A method that uses a next-generation sequencer to simultaneously determine the base sequences of a huge number of DNA fragments.
The purpose of this study is to analyze BRAF gene V600E mutations, EGFR gene mutation, HER2(ERBB2 gene mutations, ALK fusion gene, ROS1 fusion gene, and RET fusion gene in genomic DNA and RNA extracted from cancer tissues to determine the indications for the drugs listed in the attached table for patients with non-small cell lung cancer.
Available for pickup is Monday-Friday.
Please make sure that the material contains the tumor site before submitting it.
Please avoid duplicate requests of other items. Since this test method is more susceptible to contamination, please handle the specimens with care when collecting them.
When requesting this test, please be sure to also request the nucleic acid extraction item (item code No.: M961 0).
●About materials other than tissues
Please place the collected pleural fluid, alveolar lavage fluid, and bronchial lavage fluid for abrasion in the designated container (ARR), centrifuge (760G (2000-3000rpm) x 10 minutes) at room temperature, remove as much of the supernatant as possible, and submit the sediment after freezing it.
●Notes
After collecting the specimen, please process it immediately. Please note that if the number of cells in the submitted specimen is low, the test may not be possible.
滅菌ポリスピッツ
貯蔵方法:室温
遺伝子変異等 | がん腫 | 関連する医薬品 |
---|---|---|
BRAF 遺伝子V600E変異 | 非小細胞肺癌 | ダブラフェニブメシル酸塩及びトラメチニブジメチルスルホキシド付加物の併用投与 |
EGFR遺伝子変異 | ゲフィチニブ、エルロチニブ塩酸塩、アファチニブマレイン酸塩、オシメルチニブメシル酸塩、ダコミチニブ水和物 | |
HER2(ERBB2)遺伝子変異 | トラスツズマブ デルクステカン(遺伝子組換え) | |
ALK融合遺伝子 | クリゾチニブ、アレクチニブ塩酸塩、ブリグチニブ、ロルラチニブ | |
ROS1融合遺伝子 | クリゾチニブ、エヌトレクチニブ | |
RET融合遺伝子 | セルペルカチニブ |