Laboratory:Akiruno
- TOP
- gene-related test
- genetic tests for malignant tumor (solid tumor)
- Lung cancer compact panel for research(Suspended beyond orders placed 03-29-2024)
Laboratory:Akiruno
○Lung cancer compact panel for research(Suspended beyond orders placed 03-29-2024)
CODE:00Q70 7
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TEST NAME
SPECIMEN
REQUIREMENT
(mL) CONTAINER CAP COLOR STORE
TEMPERATURE
(STABILITY) TURNAROUND
TIME (DAY) METHODOLOGY REFERENCE RANGE
(UNIT) -
Lung cancer compact panel for research(Suspended beyond orders placed 03-29-2024)
Cytodiagnosis materials
1mg
X90
(14 days)
8-15 Next Generation Sequencing (NGS)A method that uses a next-generation sequencer to simultaneously determine the base sequences of a huge number of DNA fragments.
COMMENT
The purpose of this study is to detect EGFR gene mutation, ALK fusion gene, ROS1 fusion gene, and MET ex14 skipping mutation using nucleic acids extracted from cancer tissues to determine the indication of drugs for non-small cell lung cancer.
The percentage of tumor cells required for testing is 10% or more. Please see below for notes on submitting unstained specimen slides. In addition, when submitting specimens, please follow the detailed information for specimen submission in the product pamphlet issued by DNA Chip Research Laboratories.
Please avoid duplicate requests with other items. Since this test method is more susceptible to contamination, please handle the specimens with care when collecting them.
※To request this inspection, an account registration application is required.
●When requesting this inspection
Please submit specimens according to the detailed information for specimen submission in the product pamphlet issued by the DNA Chip Research Institute.
Unstained specimen slides should be histopathologically evaluated to ensure that tumor cells are present in a proportion greater than that required for testing.
●About unstained specimen slides
The collected tissue should be immediately immersed in a 10% neutral buffered formalin solution for fixation (Recommended immobilization time is 6-48 hours). When submitting, please prepare serial sections of the specified thickness from formalin-fixed, paraffin-embedded (FFPE) blocks made within the last 3 years whenever possible. Please be careful to avoid contamination by changing the microtome blade for each specimen during thin sectioning. Additionally, please note that since nucleic acids are fragmented by formalin fixation of tissues, analysis may not be possible depending on the type and composition of the fixation solution, fixation time, and storage conditions of the specimens after fixation.
●About biopsy specimens
Please note that biopsy specimens are often m
CONTAINER
X90 旧容器記号 L7
核酸保存容器「GM管」
内容:核酸庇護剤
貯蔵方法:室温
有効期限:製造から1年
supplementary information
対象遺伝子変異等と関連する医薬品および適応がん腫
遺伝子変異等 | がん腫 | 関連する医薬品 |
---|---|---|
EGFR遺伝子変異 | 非小細胞肺癌 | ゲフィチニブ、エルロチニブ塩酸塩、アファチニブマレイン酸塩、オシメルチニブメシル酸塩 |
ALK融合遺伝子 | クリゾチニブ、アレクチニブ塩酸塩、ブリグチニブ | |
ROS1融合遺伝子 | クリゾチニブ | |
METex14スキッピング変異 | テポチニブ塩酸塩水和物 |