TEST DIRECTORY

Submitting samples for tests of estrogen receptor / progesterone receptor, IHC, breast cancer HER2/neu protein, staining method, and breast cancer HER2 gene, FISH

• These tests are performed to help determine the course of treatment for a case with definitive pathological diagnosis. Please provide the pathological diagnosis and histological type in the pathology request form to put in your request.
• In some cases, the presence/absence of cancer cells and histological type may not be clear; please provide a copy of a certificate of pathological diagnosis when putting in your request. (It is not required if SRL has conducted the general pathology.)
  If for some reasons you are unable to provide a copy of a certificate, please provide as many specifics as possible such as the pathological diagnosis (e.g. histological type) and clinical information in the pathology request form.
• For a testing material, provide paraffin-embedded blocks that have been fixed in 10% neutral buffered formalin fixative for about 24 to 48 hours. Wrap the paraffin blocks in gauze, etc., and place in a plastic bag, etc. before submitting them, to prevent them from being damaged.
• We accept requests using fixed tissues and unstained slides; please keep in mind the following:
  • For fixed tissues, put in your request also for the block preparation [Code No.: 05651 3] [Code No.: 5651 6] at the same time.
  • For unstained slides, make sure you use silanized slides, as many as required according to the test name you request for (see below). Note that 9 slides will be required for 2 different codes.

    [Required number of slides when ordering with unstained slides]

    CODE	TEST NAME	NUMBER OF SLIDES
    00A08 2 0A08 4	Estrogen receptor, IHC	4
    00A12 7 0A12 6	Progesterone receptor, IHC	4
    00A16 3 0A16 5	Estrogen receptor/progesterone receptor, IHC	6
    00A20 8 0A20 7	Breast cancer HER2/neu protein, staining method	4
    00A28 0 0A28 5	Breast cancer HER2 gene, FISH	4

• If you are requesting tests for breast cancer HER2 gene, FISH and breast cancer HER2/neu protein, staining method has already been performed, please provide the test results for the latter in the pathology request form.