Laboratory：Akiruno
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- Amikacin
Laboratory：Akiruno
○Amikacin
CODE：00784 1
-
TEST NAME
SPECIMEN
REQUIREMENT
（ｍL） CONTAINER CAP COLOR STORE
TEMPERATURE
(STABILITY) TURNAROUND
TIME (DAY) METHODOLOGY REFERENCE RANGE
(UNIT) BLOOD COLLECTION TIME -
Amikacin
Serum
0.4
S7P
↓
A00
2-4 KIMSPeak 50-60KIMS (Kinetic Interaction of Microparticles in Solution)
A method in which an antigen-antibody reaction is performed using microparticles bound to antigens or antibodies, and the turbidity of the agglutination caused by the antigen-antibody reaction is measured from the transmittance by irradiating it with light.
Trough Less than 4
(μg/mL)
See below 1 hour after the start of the infusion (30 minutes after the end if administered in 30 minutes) (Peak concentration)
Within 30 minutes before administration (Trough concentration)
COMMENT
Be careful cross-reaction with arbekacin.
Amikamycin,
Biklin
Points to note concerning blood collecting containers
Avoid using a container with a serum separating agent. It may effect the results on the drug tests.
Points to note concerning the blood collecting time
1. The blood collecting time is for TDM (therapeutic drug monitoring).
2. In repetitive administration, collect a blood sample after a steady state is achieved.
3. When poisoning is developed, the peak concentration also needs to be measured.
4. The blood collecting time shows the standard time: a patient's condition should be taken into account in collecting a blood sample.
CONTAINER
S7P 旧容器記号 C4 X2 X1
分離剤なし (真空採血量7mL)
貯蔵方法：室温
有効期間：製造から1年
A00 旧容器記号 X
ポリスピッツ
貯蔵方法：室温
supplementary information
グラム陰性菌感染症に対する標準治療における目標値
| 最小発育阻止濃度 (MIC) | 8μg/mL (重症) | ≦4μg/mL (軽・中等症) | ||
| アミカシン | Peak 50 〜60 |
Trough 4未満 |
Peak 41 〜49 |
Trough 4未満 |
| 最小発育阻止濃度 (MIC) | 2μg/mL (重症) | ≦1μg/mL (軽・中等症) | ||
| ゲンタマイシン | Peak 15 〜20 |
Trough 1未満 |
Peak 8 〜10 |
Trough 1未満 |
| トブラマイシン | ||||
※基準値は重症における目標値を基準値 (治療濃度範囲) として設定いたしました。
