Laboratory：Akiruno
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- Tobramycin
Laboratory：Akiruno
○Tobramycin
CODE：00783 2
-
TEST NAME
SPECIMEN
REQUIREMENT
（ｍL） CONTAINER CAP COLOR STORE
TEMPERATURE
(STABILITY) TURNAROUND
TIME (DAY) METHODOLOGY REFERENCE RANGE
(UNIT) BLOOD COLLECTION TIME -
Tobramycin
Serum
0.4
S7P
↓
A00
2-4 Enzyme immunoassay(EIA)Peak 15-20EIA (Enzyme immunoassay)
Enzyme immunoassay
The measurement principle is the same as RIA; an antigen-antibody reaction is performed using an enzyme-labeled antigen or antibody as a labeling substance, and a chromogenic substrate is added to detect enzyme activity. How to measure.
Trough less than 1 (μg/mL)
See below 1 hour after the start of the infusion (30 minutes after the end if administered in 30 minutes) (Peak concentration) Within 30 minutes before administration (Trough concentration)
TEST NAME | SPECIMEN | CONTAINER |
|---|---|---|
Tobramycin
|
Serum
|
CAP COLOR | STORE | TURNAROUND |
|---|---|---|
|
| 2-4 |
METHODOLOGY | REFERENCE RANGE | BLOOD COLLECTION TIME |
|---|---|---|
Enzyme immunoassay(EIA) EIA (Enzyme immunoassay) |
Peak 15-20 | 1 hour after the start of the infusion (30 minutes after the end if administered in 30 minutes) (Peak concentration) Within 30 minutes before administration (Trough concentration) |
COMMENT
Tobracin
Points to note concerning blood collecting containers
Avoid using a container with a serum separating agent. It may effect the results on the drug tests.
Points to note concerning the blood collecting time
1. The blood collecting time is for TDM (therapeutic drug monitoring).
2. In repetitive administration, collect a blood sample after a steady state is achieved.
3. When poisoning is developed, the peak concentration also needs to be measured.
4. The blood collecting time shows the standard time: a patient's condition should be taken into account in collecting a blood sample.
CONTAINER
S7P
Not containing separating agent (7mL vacuum blood sampling tube)
Storage method: Room temperature
Expiration period: 1 year from production
A00 Previous container symbol X
Polyethylene test tube
Storage method: Room temperature
supplementary information
グラム陰性菌感染症に対する標準治療における目標値
| 最小発育阻止濃度 (MIC) | 8μg/mL (重症) | ≦4μg/mL (軽・中等症) | ||
| アミカシン | Peak 50 〜60 |
Trough 4未満 |
Peak 41 〜49 |
Trough 4未満 |
| 最小発育阻止濃度 (MIC) | 2μg/mL (重症) | ≦1μg/mL (軽・中等症) | ||
| ゲンタマイシン | Peak 15 〜20 |
Trough 1未満 |
Peak 8 〜10 |
Trough 1未満 |
| トブラマイシン | ||||
※基準値は重症における目標値を基準値 (治療濃度範囲) として設定いたしました。
