TEST DIRECTORY

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Laboratory:Akiruno

Tobramycin

  • TEST NAME SPECIMEN
    REQUIREMENT
    (mL)
    CONTAINER CAP COLOR STORE
    TEMPERATURE
    (STABILITY)
    TURNAROUND
    TIME (DAY)
    METHODOLOGY REFERENCE RANGE
    (UNIT)
    BLOOD COLLECTION TIME
  • Tobramycin
    Serum
    0.4
    S7P

    A00
    Freeze
    2-4 Enzyme immunoassay(EIA)

    KIMS (Kinetic Interaction of Microparticles in Solution)
    A method in which an antigen-antibody reaction is performed using microparticles bound to antigens or antibodies, and the turbidity of the agglutination caused by the antigen-antibody reaction is measured from the transmittance by irradiating it with light.

    Peak 15-20
    Trough less than 1 (μg/mL)
    See below
    1 hour after the start of the infusion (30 minutes after the end if administered in 30 minutes) (Pea

COMMENT


Tobracin
Precautions regarding blood collection containers
Avoid using containers containing serum separating agents. It may affect the measured values in drug tests.
Notes on blood sampling time
1. Blood sampling time for TDM (blood drug concentration monitor).
2. For continuous administration, collect blood after reaching a steady state.
3. Peak concentration must also be measured at the time of poisoning.
4. This is a standard time, and it is preferable to draw blood according to the patient's situation.

CONTAINER

supplementary information



グラム陰性菌感染症に対する標準治療における目標値

(単位:μg/mL)
最小発育阻止濃度 (MIC) 8μg/mL (重症) ≦4μg/mL (軽・中等症)
アミカシン Peak
50 〜60
Trough
4未満
Peak
41 〜49
Trough
4未満
最小発育阻止濃度 (MIC) 2μg/mL (重症) ≦1μg/mL (軽・中等症)
ゲンタマイシン Peak
15 〜20
Trough
1未満
Peak
8 〜10
Trough
1未満
トブラマイシン
抗菌薬TDMガイドライン2016より改変

※基準値は重症における目標値を基準値 (治療濃度範囲) として設定いたしました。

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