Laboratory:Akiruno
- TOP
- gene-related test
- genetic tests for malignant tumor (solid tumor)
- Oncomine Dx Target Test Multi-CDx System 4-Gene Analysis (FFPE)(Suspended beyond orders placed 12-28-2021)
Laboratory:Akiruno
○Oncomine Dx Target Test Multi-CDx System 4-Gene Analysis (FFPE)(Suspended beyond orders placed 12-28-2021)
CODE:0R611 5
-
TEST NAME
SPECIMEN
REQUIREMENT
(mL) CONTAINER CAP COLOR STORE
TEMPERATURE
(STABILITY) TURNAROUND
TIME (DAY) METHODOLOGY REFERENCE RANGE
(UNIT) -
Oncomine Dx Target Test Multi-CDx System 4-Gene Analysis (FFPE)(Suspended beyond orders placed 12-28-2021)
Unstained specimen slide
15 pieces
Z10
7-11 Next Generation Sequencing (NGS)
COMMENT
DNA and RNA extracted from cancer tissue are analyzed to determine the indications for the following drugs for patients with non-small cell lung cancer.
The percentage of tumor cells required for testing is 30% or more. Please see the following for notes on submitting unstained specimen slides.
Please avoid duplicate requests with other items. Since this test method is more susceptible to contamination, please handle the specimens with care when collecting them.
When requesting this test, please be sure to also request the nucleic acid extraction item (item code No. M951 4).
●About submission conditions
Unstained specimen slides should be histopathologically evaluated to ensure that the tumor cells are present in at least the required percentage for examination.If the tumor cell percentage is not met, mark the tumor cell area from the back of the unstained specimen slide. Please be aware that if the specimens are submitted without marking, macrodissection cannot be performed, which may affect the results, such as a false negative result.
●About unstained specimen slides
The collected tissue should be immediately immersed in a 10% neutral buffered formalin solution for fixation (recommended fixation time: 6-48 hours). When submitting, please prepare serial sections of the specified thickness from formalin-fixed, paraffin-embedded (FFPE) blocks made within the last three years if possible. Please be careful to avoid contamination by changing the microtome blade for each specimen during thin sectioning. Additionally, Please note that since nucleic acids are fragmented by formalin fixation of tissues, analysis may not be possible depending on the type and composition of the fixation solution, fixation time, and storage conditions of the specimens after fixation..
●About biopsy specimens
Please note that biopsy specimens are often minute amounts of specimen, and the tissue itself may be almost lost or may be a piece of tissue that co
CONTAINER
Z10 旧容器記号 t 30
[オブジェクトケース]
プレパラート (スライドグラス)
貯蔵方法:室温
supplementary information
対象遺伝子変異等と関連する医薬品
BRAF V600E変異 | ダブラフェニブメシル酸塩及びトラメチニブ ジメチルスルホキシド付加物の併用投与 |
---|---|
EGFR L858R変異および EGFRエクソン19欠失変異 |
ゲフィチニブ、エルロチニブ塩酸塩、アファチニブマレイン酸塩、オシメルチニブメシル酸塩 |
ALK融合遺伝子 | クリゾチニブ、アレクチニブ塩酸塩 |
ROS1融合遺伝子 | クリゾチニブ、エヌトレクチニブ |